Efficacy and safety of retrobulbar amphotericin B injection in invasive fungal rhinosinusitis with orbital invasion patients

Background: At present, there is no consensus for optimal orbital infection management in invasive fungal rhinosinusitis patients. This the first retrospective cohort study aimed to determine efficacy and side effects of retrobulbar amphotericin B injection Methodology: A chart review was conducted from 2005 2020. Thirty-six patients (forty-two orbits) diagnosed with invasion, treated or without injection, were included study. Results: There a total 36 study, 12 received 24 did not. significant difference exenteration death between two groups. Visual acuity change at 3rd month significantly better exposure group. overall clinical outcome 12th month. report severe all Conclusions: Retrobulbar showed stabilizing even improving visual any effects. procedure should be considered as adjunctive treatment.